All canine cells are full of very busy machines called mitochondria that produce almost all the dog’s energy. They are especially busy in brain cells. Though the canine brain is small compared to its body, it uses a quarter of all your dog’s energy. If you are going to optimize brain function, then you have to provide substrates for that energy production. One Important substrate is Co-enzyme Q10, which we have included along with other important synergists in ON!
Coenzyme Q10 is a key component of the mitochondrial electron transport chain which makes the energy molecule, ATP, in dogs, and in us. Deficiency of this nutrient leads to fatigue and depression-like symptoms (32). Coenzyme Q10 also acts as a strong antioxidant.
Numerous animal studies indicate that supplementation with Coenzyme Q10 preserves the dopamine axis in aging animals. In doing so, it also preserves agility, balance, motor skills, and cognition, especially decision-making (33).
32. Kobayashi S, Muroyama A, Matsushima H, Yoshimura I, Mitsumoto Y. Oral administration of coenzyme Q₁₀ reduces MPTP-induced loss of dopaminergic nerve terminals in the striatum in mice. Neurol Sci. 2012 Feb;33(1):195-9. doi: 10.1007/s10072-011-0627-z.
33. Shults CW. Therapeutic role of coenzyme Q(10) in Parkinson’s disease. Pharmacol Ther. 2005 Jul;107(1):120-30.